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 ORIGINAL ARTICLE
Year : 2010  |  Volume : 20  |  Issue : 4  |  Page : 179-184

Long-term survival of living donor renal transplants: A single center study


1 Department of Epidemiology, School of Health and Nutrition, Shiraz University of Medical Sciences, Shiraz, Iran
2 Faculty of Health, Arak University of Medical Sciences, Arak, Iran
3 Shiraz Organ Transplantation Center, Namazi Hospital, Shiraz University of Medical Sciences, Shiraz, Iran
4 Department of Social Welfare, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran
5 Department of Surgery, Imam Reza Hospital, Tabriz University of Medical Sciences, Tabriz, Iran

Correspondence Address:
A A Hashiani
School of Health, Arak University of Medical Sciences, Arak
Iran
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0971-4065.73439

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Kidney transplantation is the treatment of choice for end-stage renal disease. The aim of this study was to determine the ten-year graft survival rate of renal transplantation in patients who have been transplanted from live donors. This is a historical cohort study designed to determine the organ survival rate after kidney transplantation from live donor during a 10-year period (from March 1999 to March 2009) on 843 patients receiving kidney transplant in the transplantation center of Namazi hospital in Shiraz, Iran. Kaplan-Meier method was used to determine the survival rate, log-rank test was used to compare survival curves, and Cox proportional hazard model was used to multivariate analysis. Mean follow-up was 53.07 ± 34.61 months. Allograft survival rates at 1, 3, 5, 7, and 10 years were 98.3, 96.4, 92.5, 90.8, and 89.2%, respectively. Using Cox proportional hazard model, the age and gender of the donors along with the creatinine level of the patients at discharge were shown to have a significant influence on survival. The 10-year graft survival rate of renal transplantation from living donor in this center is 89.2%, and graft survival rate in our cohort is satisfactory and comparable with reports from large centers in the world.






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Indian Journal of Nephrology
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Online since 20th Sept '07