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 CASE REPORT
Year : 2016  |  Volume : 26  |  Issue : 4  |  Page : 284-287

Lupus podocytopathy: An important differential diagnosis of nephrotic syndrome in systemic lupus erythematosus


1 Department of Nephrology, Institute of Post Graduate Medical Education and Research, Kolkata, West Bengal, India
2 Department of Nephrology, Stanley Medical College, Chennai, Tamil Nadu, India
3 Department of Pathology, Center for Renal and Urological Pathology, Chennai, Tamil Nadu, India

Correspondence Address:
A A Kurien
Department of Pathology, Center for Renal and Urological Pathology, AL 190, 1st Street, 12th Main Road, Anna Nagar, Chennai - 600 040, Tamil Nadu
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0971-4065.169566

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Some patients with systemic lupus erythematosus (SLE) present with sudden onset of nephrotic syndrome and biopsy findings may be of minimal change disease or focal segmental glomerulosclerosis with diffuse foot process effacement on electron microscopy but without significant immune deposits. This entity is termed lupus podocytopathy. Clinicians and renal pathologists need to be aware of this condition. Though steroid sensitive, it needs follow-up to recognize flare and class change, thereby optimizing therapy.






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Indian Journal of Nephrology
Published by Wolters Kluwer - Medknow
Online since 20th Sept '07