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 CASE REPORT
Year : 2017  |  Volume : 27  |  Issue : 2  |  Page : 133-135

Hemophagocytic lymphohistiocytosis secondary to hemodialysis catheter-related blood stream infection


1 Department of Nephrology, Yashoda Hospitals, Secunderabad, Telangana, India
2 Department of Laboratory Medicine, Yashoda Hospitals, Secunderabad, Telangana, India
3 Department of Clinical Hematology and Oncology, Yashoda Hospitals, Secunderabad, Telangana, India

Correspondence Address:
U Anandh
Yashoda Hospitals, Alexander Road, Secunderabad - 500 014, Telangana
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0971-4065.180604

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A 57-year-old man on dialysis presented with fever due to Pseudomonas septicemia. Workup revealed very high triglycerides and serum ferritin levels. A bone marrow examination showed hemophagocytosis. A diagnosis of hemophagocytic lymphohistiocytosis (HLH) was made and steroids were started. He was put on automated peritoneal dialysis. Patients' condition continued to deteriorate and he succumbed to his illness. This case illustrates the development of HLH secondary to infections which are increasingly being recognized in the literature. Often this diagnosis is missed as it becomes difficult to differentiate between sepsis and HLH. The presence of high ferritin, hypertriglyceridemia, and hemophagocytosis in the bone marrow confirms the diagnosis.






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Indian Journal of Nephrology
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Online since 20th Sept '07