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 CASE REPORT
Year : 2018  |  Volume : 28  |  Issue : 5  |  Page : 393-396

Late posttransplant lymphoproliferative disease: Report of a rare case and role of positron emission tomography-computed tomography


1 Department of Urology and Renal Transplantation, SGPGIMS, Lucknow, Uttar Pradesh, India
2 Department of Nuclear Medicine, SGPGIMS, Lucknow, Uttar Pradesh, India
3 Department of Nephrology, SGPGIMS, Lucknow, Uttar Pradesh, India
4 Department of Radiology, SGPGIMS, Lucknow, Uttar Pradesh, India

Correspondence Address:
H Lal
Department of Radiology, SGPGIMS, Lucknow - 226 014, Uttar Pradesh
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijn.IJN_262_17

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Posttransplant lymphoproliferative disease (PTLD) is an uncommon complication of immunosuppression after solid organ transplantation. Early PTLD (<1 year after transplantation) is frequently found around the allograft, whereas late PTLD (>1 year after transplantation) does not have such a preference. 18-Fluorodeoxyglucose positron emission tomography-computed tomography (18FDG PET-CT) has clinical significance in the evaluation of PTLD. 18FDG PET-CT scan allows precise anatomic localization of FDG-avid lesions, hence helpful in staging of disease and evaluation of response to therapy. It can better characterize persistent lesions and differentiate residual tumor from fibrosis or necrosis. We present a rare case report of a perigraft PTLD developing 12 years after renal transplantation sparing the graft, in an Epstein–Barr virus-negative patient.






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