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Official publication of the Indian Society of Nephrology
 
CASE REPORT
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Rare cause of hyperkalemia in the newborn period: Report of two cases of pseudohypoaldosteronism Type 1


 Department of Neonatology, Sri Ramachandra Medical University, Chennai, Tamil Nadu, India

Correspondence Address:
B Umamaheswari,
Department of Neonatology, Sri Ramachandra Medical University, Porur, Chennai - 600 116, Tamil Nadu
India
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Source of Support: None, Conflict of Interest: None

Pseudohypoaldosteronism (PHA) Type 1 is characterized by mineralocorticoid resistance, manifesting as neonatal salt wasting, hypotension, hyperkalemia, hyponatremia, and metabolic acidosis in spite of elevated aldosterone levels and plasma renin activity. It is important to differentiate children with systemic PHA from renal PHA, as these children are likely to decompensate even with mild symptoms. Here, we report two neonates with PHA that presented to us with multiorgan involvement.


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    -  Manipriya R
    -  Umamaheswari B
    -  Prakash A
    -  Binu N
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Indian Journal of Nephrology
Published by Wolters Kluwer - Medknow
Online since 20th Sept '07