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Official publication of the Indian Society of Nephrology
 
LITERATURE REVIEW
Ahead of Print

Reset osmostat: Facts and controversies


 Department of Physiology, University Institute of Hospital Italiano de Buenos Aires, Argentina

Correspondence Address:
CG Musso,
Department of Physiology, University Institute of Hospital Italiano De Buenos Aires, Potosí 4234, C1199ACL. Ciudad de Buenos Aires
Argentina
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijn.IJN_307_17

Reset osmostat (RO) consists of a change in the normal plasma osmolality threshold (reduction or increase), which consequently induces chronic dysnatremia (hyponatremia or hypernatremia). Although the early papers on RO state that hyponatremic patients with this condition are usually not symptomatic, the current view is that most patients with hyponatremia are symptomatic and should be treated. RO has been associated with a myriad of clinical conditions and has clear diagnostic criteria which are crucial to arrive at the correct diagnosis and treatment.


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    -  Feder J
    -  Gomez J M
    -  Serra-Aguirre F
    -  Musso C G
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Indian Journal of Nephrology
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