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Year : 2016  |  Volume : 26  |  Issue : 2  |  Page : 142--144

Eosinophilic granulomatosis with polyangiitis with severe pulmonary hemorrhage treated with rituximab

S Baikunje1, M Vankalakunti2, VS Upadhyaya3, GB Hosmane4 
1 Department of Nephrology, K. S. Hegde Medical Academy, Deralakatte, Mangalore, India
2 Department of Nephropathology, Manipal Hospital, Bengaluru, Karnataka, India
3 Department of Radiology, K. S. Hegde Medical Academy, Deralakatte, Mangalore, India
4 Department of Pulmonology, K. S. Hegde Medical Academy, Deralakatte, Mangalore, India

Correspondence Address:
S Baikunje
Department of Nephrology, K. S. Hegde Medical Academy, Deralakatte, Mangalore, Karnataka
India

Eosinophilic granulomatosis with polyangiitis (EGPA) is characterized by systemic vasculitis, asthma and eosinophilia. Severe pulmonary hemorrhage is rare. Renal involvement is seen in approximately 25% and can vary from isolated urinary abnormality to rapidly progressive glomerulonephritis. There is limited evidence to support the use of rituximab in this condition. We present a patient with EGPA who had severe pulmonary hemorrhage and rapidly progressive glomerulonephritis. He responded to standard treatment including prednisolone, cyclophosphamide, and plasma exchange. He subsequently had a relapse of pulmonary hemorrhage that was treated successfully with rituximab.

How to cite this article:
Baikunje S, Vankalakunti M, Upadhyaya V S, Hosmane G B. Eosinophilic granulomatosis with polyangiitis with severe pulmonary hemorrhage treated with rituximab .Indian J Nephrol 2016;26:142-144

How to cite this URL:
Baikunje S, Vankalakunti M, Upadhyaya V S, Hosmane G B. Eosinophilic granulomatosis with polyangiitis with severe pulmonary hemorrhage treated with rituximab . Indian J Nephrol [serial online] 2016 [cited 2020 Feb 18 ];26:142-144
Available from: http://www.indianjnephrol.org/article.asp?issn=0971-4065;year=2016;volume=26;issue=2;spage=142;epage=144;aulast=Baikunje;type=0