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Year : 2018  |  Volume : 28  |  Issue : 3  |  Page : 244--246

Perinuclear antineutrophil cytoplasmic antibody positive glomerulonephritis in a case of limited cutaneous scleroderma

H Vora1, B Kulkarni2, S Singh3, N Kulkarni1 
1 Department of Nephrology, Kokilaben Dhirubhai Ambani Hospital, Mumbai, Maharashtra, India
2 Department of Histopatholohy, Kokilaben Dhirubhai Ambani Hospital, Mumbai, Maharashtra, India
3 Department of Rheumatology, Kokilaben Dhirubhai Ambani Hospital, Mumbai, Maharashtra, India

Correspondence Address:
H Vora
Kokilaben Dhirubhai Ambani Hospital, Mumbai, Maharashtra
India

Antineutrophil cytoplasmic antibody (ANCA)-associated glomerulonephritis in a patient of scleroderma is very rare. Very few cases have been reported in English literature. We report a case of a 58-year-old male with long-standing limited cutaneous scleroderma (Scl-70 positive) presenting with normotensive scleroderma renal crisis. Perinuclear ANCA with antimyeloperoxidase antibody was found to be strongly positive. Renal biopsy showed pauci immune-necrotizing crescentic glomerulonephritis. We believe that this case report will be helpful in understanding clinical features of normotensive ANCA-associated glomerulonephritis in scleroderma patients.

How to cite this article:
Vora H, Kulkarni B, Singh S, Kulkarni N. Perinuclear antineutrophil cytoplasmic antibody positive glomerulonephritis in a case of limited cutaneous scleroderma.Indian J Nephrol 2018;28:244-246

How to cite this URL:
Vora H, Kulkarni B, Singh S, Kulkarni N. Perinuclear antineutrophil cytoplasmic antibody positive glomerulonephritis in a case of limited cutaneous scleroderma. Indian J Nephrol [serial online] 2018 [cited 2020 Apr 9 ];28:244-246
Available from: http://www.indianjnephrol.org/article.asp?issn=0971-4065;year=2018;volume=28;issue=3;spage=244;epage=246;aulast=Vora;type=0