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Year : 2011  |  Volume : 21  |  Issue : 1  |  Page : 41-43

Effective use of polymyxin B hemoperfusion in septic shock complicated by urosepsis

Department of Nephrology, Lilavati Hospital and Research Centre, Mumbai, India

Correspondence Address:
P Malleshappa
Senior Registrar, Department of Nephrology, A-791, Lilavati Hospital and Research Centre, Bandra Reclamation, Bandra (W), Mumbai-400 050, Maharashtra
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0971-4065.78077

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Direct hemoperfusion using polymyxin B-immobilized fiber (PMX-DHP) is an established treatment method for septic shock caused by Gram-negative infections. Here we report one instance in which PMX-DHP therapy has been used successfully in a patient with septic shock from urosepsis. After antibiotic therapy, direct hemoperfusion using polymyxin B helped in cardiovascular stability. The patient recovered from the shock within a few days after treatment with polymyxin-B hemoperfusion. As far as we are aware, this is the first reported case of effective treatment of urosepsis complicated by septic shock using PMX-DHP therapy in India.


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Indian Journal of Nephrology
Published by Wolters Kluwer - Medknow
Online since 20th Sept '07