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Year : 2011  |  Volume : 21  |  Issue : 1  |  Page : 52-55

Collagenofibrotic glomerulopathy - Case report with review of literature

1 Department of Nephrology,Medwin Hospital, Hyderabad, India
2 Department of Nephrology, Osmania Medical College, Hyderabad, India
3 Department of Pathology, Apollo Hospital, Hyderabad, India

Correspondence Address:
K C Patro
C/O Dr. Ratan Jha, Department of Nephrology, Medwin Hospital, Hyderabad
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0971-4065.78080

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Collagenofibrotic glomerulopathy is a rare, idiopathic glomerular disease characterized by abnormal accumulation of type III collagen fibrils within the mesangial matrix and subendothelial space and a marked increase in serum type III procollagen peptide levels. Proteinuria (commonest feature), edema, hypertension, and occasional progression to end-stage renal disease are the various features of this disease. The etiology and pathogenesis remain elusive. There have been reports of the disease running in the family, suggesting the possibility of genetic transmission. We report two cases of this rare entity.


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Indian Journal of Nephrology
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Online since 20th Sept '07