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 CASE REPORT
Year : 2013  |  Volume : 23  |  Issue : 3  |  Page : 222-225

Syndrome of rapid-onset end-stage renal disease in two consecutive renal transplant recipients


Department of Medicine, College of Medicine, Mayo Clinic, Rochester, MN, and Nephrology, Mayo Clinic Health System Eau Claire, 1221 Whipple Street, Eau Claire, WI 54702, USA

Correspondence Address:
M A Onuigbo
Department of Nephrology, Mayo Clinic Health System Eau Claire, 1221 Whipple Street, Eau Claire, WI 54702
USA
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0971-4065.111861

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A syndrome of rapid-onset end-stage renal disease (SORO-ESRD) following acute kidney injury (AKI) in native kidneys was described recently. To what extent this syndrome of unanticipated and rapidly irreversible ESRD impacts renal allograft survival is unknown. Over 6 months, we managed two deceased donor renal transplant recipients (RTRs) with rapid acceleration of previously stable allograft chronic kidney disease to abruptly terminate in irreversible ESRD following AKI. These are the first reports of SORO-ESRD in RTRs. More research is needed to ascertain the contribution of SORO-ESRD to renal allograft loss.






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Indian Journal of Nephrology
Published by Wolters Kluwer - Medknow
Online since 20th Sept '07