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Year : 2013  |  Volume : 23  |  Issue : 4  |  Page : 308-311

IgG4 related interstitial nephritis: A case report and review of literature

1 Department of Nephrology, Madras Medical College and Rajiv Gandhi Government General Hospital, Chennai, India
2 Consultant Nephropathologist, Madras Medical Mission, Chennai, India

Correspondence Address:
N Gopalakrishnan
Department of Nephrology, Madras Medical College and Rajiv Gandhi Government General Hospital, Chennai - 600 003
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0971-4065.114489

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IgG4 interstitial nephritis is a recently described entity. A middle-aged gentleman with bilateral parotid enlargement, hepatosplenomegaly and generalized lymphadenopathy was referred to us for evaluation of renal failure. He had trace proteinuria and large kidneys. Kidney biopsy revealed interstitial nephritis with characteristic storiform fibrosis. Immunohistochemistry demonstrated intense staining for IgG4-secreting plasma cells in the interstitium.


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Indian Journal of Nephrology
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Online since 20th Sept '07