IgG4 related interstitial nephritis: A case report and review of literature

N Gopalakrishnan; A Abraham; T Balasubramaniyan; T Dineshkumar; J Dhanapriya; N Malathy; M Haris; ND Srinivasa Prasad

doi:10.4103/0971-4065.114489

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CASE REPORT

Year : 2013 | Volume : 23 | Issue : 4 | Page : 308-311

IgG4 related interstitial nephritis: A case report and review of literature

N Gopalakrishnan¹, A Abraham², T Balasubramaniyan¹, T Dineshkumar¹, J Dhanapriya¹, N Malathy¹, M Haris¹, ND Srinivasa Prasad¹
¹ Department of Nephrology, Madras Medical College and Rajiv Gandhi Government General Hospital, Chennai, India
² Consultant Nephropathologist, Madras Medical Mission, Chennai, India

Correspondence Address:
N Gopalakrishnan
Department of Nephrology, Madras Medical College and Rajiv Gandhi Government General Hospital, Chennai - 600 003
India

Source of Support: None, Conflict of Interest: None

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DOI: 10.4103/0971-4065.114489

IgG4 interstitial nephritis is a recently described entity. A middle-aged gentleman with bilateral parotid enlargement, hepatosplenomegaly and generalized lymphadenopathy was referred to us for evaluation of renal failure. He had trace proteinuria and large kidneys. Kidney biopsy revealed interstitial nephritis with characteristic storiform fibrosis. Immunohistochemistry demonstrated intense staining for IgG4-secreting plasma cells in the interstitium.

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