Indian Journal of Nephrology About us |  Subscription |  e-Alerts  | Feedback | Login   
  Print this page Email this page   Small font sizeDefault font sizeIncrease font size
 Home | Current Issue | Archives| Ahead of print | Search |Instructions |  Editorial Board  

Users Online:708

Official publication of the Indian Society of Nephrology
 ~  Similar in PUBMED
 ~  Search Pubmed for
 ~  Search in Google Scholar for
 ~  Article in PDF (1,339 KB)
 ~  Citation Manager
 ~  Access Statistics
 ~  Reader Comments
 ~  Email Alert *
 ~  Add to My List *
* Registration required (free)  

   Article Figures

 Article Access Statistics
    PDF Downloaded135    
    Comments [Add]    
    Cited by others 1    

Recommend this journal


  Table of Contents  
Year : 2013  |  Volume : 23  |  Issue : 5  |  Page : 387

Polycystic horseshoe kidney

1 Department of General Medicine, Nizam's Institute of Medical Sciences, Punjagutta, Hyderabad, India
2 Department of Nephrology, Nizam's Institute of Medical Sciences, Punjagutta, Hyderabad, India

Date of Web Publication8-Aug-2013

Correspondence Address:
R Ram
Sri Venkateswara Institute of Medical Sciences, Tirupati, AP
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0971-4065.116337

Rights and Permissions

How to cite this article:
Prasad A K, Ram R, Swarnalatha G, Shetty M, Naidu G D, Dakshinamurty K V. Polycystic horseshoe kidney. Indian J Nephrol 2013;23:387

How to cite this URL:
Prasad A K, Ram R, Swarnalatha G, Shetty M, Naidu G D, Dakshinamurty K V. Polycystic horseshoe kidney. Indian J Nephrol [serial online] 2013 [cited 2023 Feb 5];23:387. Available from:

A 34-year-old man was admitted with a history of fever, chill, rigor, and dysuria for 15 days. There was a history of abdominal pain in the right and left lumbar regions and in the hypogastric regions for 1 week. There was a history of vomiting for 4 days. Investigations revealed blood pressure of 120/80 mmHg, pulse rate 100 beats/min and oral temperature was 104°F. On examination, there was tenderness in all quadrants of the abdomen. Cardiovascular and respiratory system examination was unremarkable. Investigations revealed fasting blood glucose 107 mg/dL, serum creatinine 1.2 mg/dL, blood urea 78 mg/dL, serum sodium 134mEq/L, serum potassium 4.2 mEq/L, alanine transaminase 15 U/L, aspartate transaminase 21 U/L, serum alkaline phosphatase 263 U/L, bilirubin 0.6 mg/dL, serum proteins 7.5 g/dL, serum albumin 3.9 g/dL, haemoglobin 14.4 g/dL, total leukocyte count 15,200/cu. mm, differential cell count P70, L25, M4, E1%, platelet count 5.4 lakhs/, urine examination pH 5.00, specific gravity 1,030, albumin 2+, sugar nil, ketones negative, red blood cells nil, White blood cells 2-3/hpf, blood and urine cultures  Escherichia More Details coli. Ultrasound of the abdomen and computed tomography (CT) scan of the abdomen showed polycystic horse shoe kidney [Figure 1]. CT of the abdomen revealed cysts in the liver and spleen. The patient was treated according to the antibiogram. At 4 weeks, he was asymptomatic and serum creatinine was 1.4 mg/dL.
Figure 1: Contrast-enhanced computed tomography scan of the abdomen shows multiple cysts in both kidneys suggestive of polycystic kidney disease. An isthmus joining the two kidneys anterior to the vertebrae is clearly visible. The isthmus also is riddled with cysts

Click here to view

About 20 patients of polycystic horseshoe kidney have been reported in the literature. [1],[2] It is thought to represent two separate renal diseases. Horseshoe kidney is a renal fusion anomaly during embryogenesis; autosomal dominant polycystic kidney disease (ADPKD) is a hereditary disorder due to mutations in the genes responsible for the expression of the proteins polycystin 1 (ADPKD1) and polycystin 2 (ADPKD2). Horseshoe kidney occurs in 1 per 400-800 live births and ADPKD in 1 in 400-1,000 live births. Polycystic horseshoe kidney occurs 1 in 134 000 to 1 in 8 000 000 live births. [2] To date, no genetic association has been described between the ADPKD loci (PKD1 on chromosome 16 and PKD2 on chromosome 4) and horseshoe kidneys.

  References Top

1.Ram R, Swarnalatha G, Santhosh Pai BH, Dakshinamurty KV. Polycystic horseshoe kidney. Clin Kidney J;2013:6(1):103-04.  Back to cited text no. 1
2.Batista Peres LA, Leonel Ferreira JR, Alvares Delfino VD. Polycystic horseshoe kidney. Nephrol Dial Transplant 2007;22:652-3.  Back to cited text no. 2


  [Figure 1]

This article has been cited by
1 Horseshoe Kidney in Conjunction With Autosomal Dominant Polycystic Kidney Disease: A Case Report
Dakota Philo
Journal of Diagnostic Medical Sonography. 2021; 37(3): 298
[Pubmed] | [DOI]


Print this article  Email this article


Indian Journal of Nephrology
Published by Wolters Kluwer - Medknow
Online since 20th Sept '07