Indian Journal of Nephrology About us |  Subscription |  e-Alerts  | Feedback | Login   
  Print this page Email this page   Small font sizeDefault font sizeIncrease font size
 Home | Current Issue | Archives| Ahead of print | Search |Instructions |  Editorial Board  

Users Online:112

Official publication of the Indian Society of Nephrology
 ~  Similar in PUBMED
 ~  Search Pubmed for
 ~  Search in Google Scholar for
 ~  Article in PDF (318 KB)
 ~  Citation Manager
 ~  Access Statistics
 ~  Reader Comments
 ~  Email Alert *
 ~  Add to My List *
* Registration required (free)  


 Article Access Statistics
    PDF Downloaded118    
    Comments [Add]    

Recommend this journal


  Table of Contents  
Year : 2014  |  Volume : 24  |  Issue : 5  |  Page : 332-333

Metallic preparations of Ayurveda: A boon to the ailing humanity

Department of Rasa Shastra and Bhaishajya Kalpana, Institute for Post Graduate Teaching and Research in Ayurveda, Gujarat Ayurved University, Jamnagar, Gujarat, India

Date of Web Publication11-Sep-2014

Correspondence Address:
G Ruknuddin
Assistant Professor, Department of Rasa Shastra and Bhaishajya Kalpana, Institute for Post Graduate Teaching and Research in Ayurveda, Gujarat Ayurved University, Jamnagar - 361 008, Gujarat
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0971-4065.133044

Rights and Permissions

How to cite this article:
Ruknuddin G. Metallic preparations of Ayurveda: A boon to the ailing humanity. Indian J Nephrol 2014;24:332-3

How to cite this URL:
Ruknuddin G. Metallic preparations of Ayurveda: A boon to the ailing humanity. Indian J Nephrol [serial online] 2014 [cited 2022 Nov 29];24:332-3. Available from:


We read with great interest the case report entitled "acute renal failure secondary to ingestion of ayurvedic medicine containing mercury". [1] Though this article highlights newer aspects of certain drugs; there are few aspects that need to be addressed.

A drug can be panacea or poison. Drugs fulfilling the criterion of a standard drug will become panacea, if it is used properly. In contrast, a poorly prepared or manufactured drug might prove to be a poison. Classics of Ayurveda do mention the hazards of drugs that are not properly manufactured. Seers have prescribed specific processing techniques (such as Shodhana and Marana etc.) for metals and minerals that remove hazardous properties from these drugs. These processed metals/minerals are familiarly known as Bhasmas in Ayurveda and are utilized in therapeutics. There is no sufficient evidence in the appeared article to confirm the nature, contents, processing details etc., of the prescribed medicine. Based on these lacunae, one cannot group the drug under the category of "Ayurveda." Such medicines may fall under the definition of spurious or misbranded or adulterated drugs. [2]

As per the principles of Ayurveda, all the preparations are not recommended for all patients. The indications, dose, to whom to give and to whom not to give, what should be the vehicle, what are the diseases, where they are not recommended etc., are the major factors always considered by an Ayurvedic Physician before they recommend metallic products to their patients. These preparations are to be administered orally in specified quantities with great caution along with requisite Anupana (vehicles) such as ghee, milk, honey etc., In the absence of Anupana, adverse reactions are

likely. [3] Whether these guidelines were followed or not is not highlighted in the published article. Ayurvedic Physician is the registered authority, who has been trained in that specific field as per the syllabus provided by Central Council for Indian Medicine, a body of Department of AYUSH, Ministry of Health and Family Welfare, Government of India. We are not sure about the identity of the healer referred in the current study.

A huge number of studies have been carried out on the usefulness of metallic preparations. Makaradhwaja (prepared in the presence of mercury, gold and sulfur) is reported to improve the quality of life and attributed with anti-stress activity. [4] Rasa sindhura (prepared in the presence of mercury and sulfur) is proven to increase life-span and fecundity of Drosophila. [5] Certain herbomineral preparations with mercury as a component were proven to be safe and efficacious like Garbhachintamani rasa that has shown to improve hepatic functions, [6] Mahamrutyunjaya rasa is proven to be cardiotonic, [7] Arogyavardhini vati, another herbomineral preparation is found to be safer at higher therapeutic dose levels. [8] Bhasmas of Abhraka (mica), Mandura (iron) and herbomineral formulations such as Swasa Kuthara rasa (containing mercury, sulfur) and Smriti Sagara rasa (mixture of metals) were reported to be free from genotoxicity. [9] Such reports are to be referred by the learned authors prior to targeting an age old system of medicine, the legacy of the nation.

This article indirectly clears the need of attention towards generating awareness on "Promoting rational use of medicines in particular to ayurvedic drugs." The impact of such reports in a leading scientific journal like Indian Journal of Nephrology is a serious matter as it may unnecessarily cause disrepute to the system of Ayurveda.

  References Top

1.Sathe K, Ali U, Ohri A. Acute renal failure secondary to ingestion of ayurvedic medicine containing mercury. Indian J Nephrol 2013;23:301-3.  Back to cited text no. 1
[PUBMED]  Medknow Journal  
2.Malik V. Drugs and Cosmetics Act, 1940. 18 th Updated ed. Lucknow: Eastern Book Company; 2006. p. 41.  Back to cited text no. 2
3.Kapoor RC. Some observations on the metal-based preparations in the Indian systems of medicine. Indian J Tradit Knowl 2010;9:562-75.  Back to cited text no. 3
4.Sinyorita S, Ghosh CK, Chakrabarti A, Auddy B, Ghosh R, Debnath PK. Effect of ayurvedic mercury preparation Makaradhwaja on geriatric canine-A preliminary study. Indian J Exp Biol 2011;49:534-9.  Back to cited text no. 4
5.Dwivedi V, Anandan EM, Mony RS, Muraleedharan TS, Valiathan MS, Mutsuddi M, et al. In vivo effects of traditional ayurvedic formulations in Drosophila melanogaster model relate with therapeutic applications. PLoS One 2012;7:e37113.  Back to cited text no. 5
6.Bulbul J, Obayed U, Rahaman MA, Rahman KA, Paul AK, Choudhuri MSK. Effect of garbha cintamani rasa-An ayurvedic formulation on lipid profile, liver function and kidney function parameters of rat plasma after chronic administration. Eur J Sci Res 2009;32:25-32.  Back to cited text no. 6
7.Rai PD, Rajput SJ. Biological evaluation of polyherbal ayurvedic cardiotonic preparation "Mahamrutyunjaya rasa". Evid Based Complement Alternat Med 2011;1-11.  Back to cited text no. 7
8.Kumar G, Srivastava A, Sharma SK, Gupta YK. Safety evaluation of an ayurvedic medicine, arogyavardhini vati on brain, liver and kidney in rats. J Ethnopharmacol 2012;140:151-60.  Back to cited text no. 8
9.Vardhini NV, Sathya TN, Balakrishna MP. Assessment of genotoxic potential of herbomineral preparations-Bhasmas. Curr Sci 2010;99:1096-100.  Back to cited text no. 9


Print this article  Email this article


Indian Journal of Nephrology
Published by Wolters Kluwer - Medknow
Online since 20th Sept '07