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Year : 2015  |  Volume : 25  |  Issue : 2  |  Page : 99-102

Collapsing glomerulopathy following anabolic steroid use in a 16-year-old boy with IgA nephropathy

1 Department of Pathology, Central Electron Microscopy Unit, Wellcome Trust Research Laboratory, Vellore, Tamil Nadu, India
2 Department of Nephrology, Christian Medical College, Vellore, Tamil Nadu, India

Correspondence Address:
Dr. S M Matthai
Department of Pathology, Central Electron Microscopy Unit, Wellcome Trust Research Laboratory, Christian Medical College, Vellore - 632 004, Tamil Nadu
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0971-4065.140714

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Collapsing glomerulopathy (CG) is a proliferative podocytopathy, increasingly recognized in a variety of disease conditions. We report a case of CG in a 16-year-old boy with IgA nephropathy (IgAN) who presented with acute kidney injury, marked proteinuria and hypertension following a short period of anabolic steroid use. Although CG has been associated with long-term anabolic steroid use among body builders, there is no data on the effect of anabolic steroid use in persons with underlying renal disease like IgAN. We postulate that development of CG in our patient could be temporally linked to intake of body-building steroids along with a predisposing background renal disease of IgAN.


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Indian Journal of Nephrology
Published by Wolters Kluwer - Medknow
Online since 20th Sept '07