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 CASE REPORT
Year : 2018  |  Volume : 28  |  Issue : 1  |  Page : 65-68

Type I cryoglobulinemic nephritis in a patient of monoclonal gammopathy of renal significance


1 Department of Nephrology, King Edward Memorial Hospital, Pune, Maharashtra, India
2 Department of Hematology, King Edward Memorial Hospital, Pune, Maharashtra, India
3 Department of Pathology, King Edward Memorial Hospital, Pune, Maharashtra, India

Correspondence Address:
Dr. V A Lobo
Department of Nephrology, King Edward Memorial Hospital, 489, Rasta Peth, Sardar Moodliar Road, Pune - 411 011, Maharashtra
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijn.IJN_175_16

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Monoclonal gammopathy of renal significance is a recently described entity in which a small B-cell clone not meeting the criteria for the diagnosis of multiple myeloma produces renal disease usually through deposition of a secreted monoclonal immunoglobulin. Here, we describe a case of Type I cryoglobulinemic glomerulonephritis diagnosed on a kidney biopsy and caused by a monoclonal IgM produced by a small bone marrow clone. The patient made a complete renal recovery after chemotherapy to suppress the clone.






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Indian Journal of Nephrology
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Online since 20th Sept '07