Indian Journal of Nephrology About us |  Subscription |  e-Alerts  | Feedback | Login   
  Print this page Email this page   Small font sizeDefault font sizeIncrease font size
 Home | Current Issue | Archives| Ahead of print | Search |Instructions |  Editorial Board  

Users Online:1081

Official publication of the Indian Society of Nephrology
Ahead of Print

Dialyzer first use reaction with polysulfone membrane: Moving beyond ethylene oxide

 Department of Nephrology, SH Medical Centre, Kottayam, Kerala, India

Correspondence Address:
Abraham Tharakan,
Consultant Nephrologist, SH Medical Centre, Kottayam - 686 002, Kerala
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijn.IJN_231_20

Acute anaphylactic/anaphylactoid reactions to dialyzers are uncommon. Indeed, they are thought to have decreased in incidence since the transition to more biocompatible dialyzer membranes and with the abandonment of ethylene oxide for sterilization of dialyzers. However, few recent Spanish studies suggest that the incidence actually remains the same. Here, we report two cases of dialyzer first use reactions that occurred with polysulfone dialyzers. These were not ethylene oxide sterilized dialyzers and the reactions were less intense/absent from the second reuse onwards. Both the patients were successfully dialyzed by switching to a cellulose triacetate dialyzer or by using a preprocessed dialyzer filled with renalin. Thus, the cause of the reaction could either be the primary polysulfone membrane or a leachable substance from the dialyzer.

Print this article
  Search Pubmed for
    -  Tharakan A
 Citation Manager
 Article Access Statistics
 Reader Comments
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded9    

Recommend this journal

Indian Journal of Nephrology
Published by Wolters Kluwer - Medknow
Online since 20th Sept '07